Hi Clairster,
I'd echo what i hate hills says. In fact, I'd go a bit further and say that you _must_ take it easier than you normally would for the first 8 miles. Don't get carried away on the flat / downhill section from mile 3 to mile 8. This is because at mile 8.5-ish, you come up against the mother of all hills (700 feet of vertical height gain), which goes up continuously from mile 8.5 to mile 11.5. If you're tired at the start of this climb, you'll be much more trouble 20 minutes later! I made this mistake the first time I ran Eyam, and experienced pain like I've never known on any previous race.
But tactics aside, I'm running Eyam for the third year in a row, and it's my favourite course - beautiful views and friendly crowd. I'll have been drinking all night the previous evening, due to a stag do, however, so I'll be taking it easy this time around!