Stair running is quite a big thing in the US, I believe.
I read something about it that recommended that you make full use of the handrail to assist your climb.
Despite running regularly, I still get puffed walking up four flights, so I'll be giving it a miss. That and the £30 entry fee.
At least this one only "suggests" a minimum fundraising of £150. The NSPCC one has a "minimum" sponsorship requirement of £250 per person. Not sure how they enforce that, though.