Been running in F-lite 195s the past year all on trails. Heel has been fine, but have been using the Bridgedale CoolFusion socks and feel great.
An ultra runner mate of mine recommended Drymax Trail lite socks - he did the Hardrock 100 in them and said they are phenomenal and really come into their own in the wet areas.
Just bought a couple of pairs from the ultramarathonrunning.com shop and tried them out for circuit training this evening and they felt great.