I am on my second pair.
They do take a while to adapt to. However, since switching my times have dropped dramatically (5mins of my 5Km) but that could be a consequence of training (going from half to full marathon). Also, have not been injured.
The wet can be a problem but only on a low grip surface. Wet tarmac is fine, getting caught in the snow was interesting. Off road is ok in the dry, but the lugs can pick up stuff but it soon drops out. Currently waiting for there off road versions to be released.
Both my kids have also switch to them and are getting on fine. That was an expensive shopping trip, 3 pairs of Newtons,