To calculate your net calorie burn per mile multiply your weight in pounds by .63
= 105 * .63 = 66
See http://www.runnersworld.com/weight-loss/how-many-calories-are-you-really-burning-0?page=single
An average woman needs 2,000 calories per day to maintain weight, although that figure could be lower for you... But you'll know that. Assuming you run on average 10k 4.5 times per week then I'd calculate that you'll be burning
= 10 * 4.5 / 1.60934 * 66 = 1845.5 extra calories.