I'm no expert either but I have had that sensation also. It was when I was overtraining and my legs would burn when I went upstairs, mainly in the thigh area. Now I have cut back and am following a more sensible training routine i.e. more structured with more rest days, I dont suffer as much and when it does come on after going up the stairs the sensation goes away after a few seconds. What sort of mileage are you doing, how long have you been running for ?