RB, I have occasional "bouts" with my back, when I get pain that can best be described as toothache of the left leg! However, it abates. With proper back management, I have been able to continue life as normal for the most part. At the moment, that injury is the least of my worries, anyway - I seem to have a million others!
BTW - L5/S1 is about the most common area for back injuries and a spondylolisthesis is dead common, too - especially among people who have done things like dance, gymnastics, diving, figure skating, etc. - all the "bendy" things. There are loads of us about.