I am having problems with a pair of 2080's. I have worn Asics for most of my running since 97 with no problems. But for no apparent reason inside and back of ankle hurts, ran on it, but it seemed to improve as i ran, until next day when it swelled up, rested for 12 days and took anti inflammatories. The problem is still there, went to sports injury clinic thinking it might be achilles tendonnitis, however, they think I may be fortunate enough for it to just be a swollen bursar (i think I have spelt that right) they still recommend resting from running but cycling is ok. But the Asics 2080's have been nothing but trouble and I will think very carefully before buying another pair. I run with orthotics and these did not suit them at all. Anyone got any recommendations in this area, I have not got a clue where to start looking for different shoe???