Roz - I'm so glad you started this thread because I've just had orthotics made and at first, they really hurt. After a few runs in them I felt I was running on bruises. My podiatrist has now shaved away some of the arch support, which was too high, so I'll see how they work out now. He's advised me to walk in them before running, as Flatfeet has suggested. And he'll fine tune them again if neccessary. He also pointed out that with the orthotics inside them, my running shoes are now a size too small, which I guess was part of what made the orthotics so uncomfortable. I do hope you get used to them...