You could try Sorbathhane insoles, I had the same problem a couple of years ago and they really helped, the extra thick socks really wont make any difference, its proabably inflamation of the bones that make up the joints under the big toe rather than hard skin
Or if you haven't done so already, go to a specialist running shop and check you are running in the right shoes
Edited: 18/03/2013 at 09:20