It also sounds like an injury I had, which isn't ITBS. If there is any numbness around the knee (as well as the pain - if that makes sense), you might have tweaked the peroneal nerve which runs down the outside of the knee. If so, some stretches and gentle massage sorted mine out.
The stretches were firstly, while sitting on a chair, place your foot in a position, off the ground, a bit like you were twisting your ankle, and rotate your ankle round inwards as far as is comfortable. Secondly, with a standing up, straighten the painful leg, with the foot on the ground, and bend the other leg to tense the painful one. Then lift your arms above your head, and throw them forward and down - this gives a bit more dynamic tension in the tensed leg. These help, but the massage (which I did myself) was simply rubbing the numbed area. Sorted itself out, and my physio said not to stop running at all.
It could be a mystery ache that will clear up with the usual rest. Give it a week, then get yourself to a doc. It sounds like it could be ITBS (Runners Knee) so you should get physio and buy a foam roller to help stretch after runs, they're magic. When you get runing again try not to get carried away and go for a full on 8 miles if you usually run 3 or 4. Just add a mile on until you feel comfortable that your fixed knee can handle it.
P.s - Don't let the doctor fob you off with pain killers and rest if you're not completely happy with what they tell you, in my experience some doctors are far from sympathetic to runners.
Having read this it confirms by IT B issue is back. Thankfully have a foam roller and it works so well the only problem is keeping using it even when there is no pain.
This for me could not have come at a worst time, marathon 2 week Sunday
Hope it clears up soon for you Wej
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