I have read through the book a couple of times now, and have read back through the forum posts on this thread. Injuries on this thread seem fairly low compared to a few other threads so I am taking that as a good sign. 
There are a couple of issues I am looking at before I make what seems like a leap of faith. Any comments appreciated.
Firstly from the very beginning of this thread there are a lot of runners struggling to hit the Interval Times. I looked at my times based on the closest I have to a 5k time (the first 3.1 miles of a half marathon that I went off much too quickly) and I think I would really struggle on those times. The tempo and LR times look fine for me, but the interval could be a big struggle. I am more used to the Mcmillan type cruise intervals which are a bit more 'relaxed'. I know this should be an intense plan, but not hitting times week after week could be soul destroying,
How do people manage this, The book recommends you only step up the pacing after all 3 key runs are being comfortably hit. I can see me plateuing
The other bit is that there is very little testimonial in the book from Sub3 runners. I scraped a sub3 in October based on 50 - 60miles pw. Injury was the main issue for me in doing this. The book does note that 2:40 runners and up have had success. Anyone got any examples or know runners who have used the plan successfully on say sub2:50 to sub 3hr?
I will either plumb for this or a modified P&D plan to introduce a bit more X/Training. I would prefer a published plan though than tinkering with something and possible unbalancing the training week.