Hi all, I thought it's about time I de-cloaked and came out of lurker status having followed this thread on-and-off since inception. In other words I thought I'd post a reply
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I've had the Advanced Marathoning book for quite a while, but couldn't make my mind up whether to follow it or not. It's mainly the higher midweek miles that I've perceived as a problem, but I've decided to make time and give it a go.
My first run was last night (18 week, up to 55m schedule) in preparation for Brighton. During my 4m threshold run, it felt uncomfortable for a couple of miles, then felt easier
In the end I had no problem completing the run and my heart rate, if anything, was a little on the low side of my threshold range.
I haven't sorted out anything for the XT days yet. So today is a rest day 
Higher midweek mileage is a change for me, so this is something of an experiment. There is so much information to take in!