Ship-star: I periodisation is not absolutely necessary, but to get the very best adaptation to marathon running its beneficial. Take Mesocyle 1 of P&D's 50-70 mile pw plan. During the first few weeks of this endurance phase, you are developing a weekend long run, and a midweek medium long run, plus a threhold run, along with a bit of easy running, a few strides and some recovery running. A heavy VO2 session during those initial weeks could really impact on your ability to handle the long stuff and develop that endurance base that you so need late into a marathon race.
You can of course train more generally, including long runs, easy runs, tempo, VO2 etc in your plan. You may enjoy the training more, but not necessarily achieve the very best time. I did my first marathon with a mixture of runs. It went well, I enjoyed the training, and may have run quicker - but who cares!