Raf
If you have a TT bike then its ideal.....
If you have a road bike add some TT bars.
The hills aren't short sharp buggers - you can stay TT ing for lots, then hoof i out of the saddle where needed.
Its not an IM Wales, ie where lots of quick gear chainging is needed.
The last third is a straight TT, (excluding the pave section)
Deep section wheels may not be such a good option..... depends on the winds, and if you get x winds on the big downhills then......
I have been busy on ebay, and now have a set of hed 6 / 9s. I dont think I'll take them out to lanza though....Last year there was a mix of disk wheels, deep sections and normal wheels........