only the one at Greding on the bottom end of the loop, but that's because you have a 90 degree left turn and the road goes up sharply from there, get in low gear to make it through that turn and the initial upswing. It's only a few hundred yards though and then it flattens out a bit, a longish climb but basically not bad. I'm the world's worst climber, if I can do it so can you. The famous Solarer Berg where huge crowds line both sides of the road is only 800m long and the cheering really helps you up it.
Really only Arizona is a flat course, but no easier from what candy and others have said as it's in the desert.
When it comes down to it, 226km is 226km, and some part of it's going to hurt no matter what the course is like. Just at Roth you have a truly tremendous crowd support right from the time of the first swim start through to the last man at the finish.