I did the half in 2013 (ok I know it's not the full one but hopefully this might still be helpful). Malta in late February is very mild - it was 16oC when I did it. Overall the course is a bit down hill so it should be quite good for a PB. You will have to register to get your numbers etc for about three days before the race (now at a hotel) in St Julians.The start is in Rabat/Mdina but you will get transport from Sliema quite early to take you there. Mdina is worth walking/jogging around before the start - it's the old capital and is tiny but beautiful and pretty much car free. I remember support was quite good at the start and towards the end but not much in the middle although I remember it being well marshalled. There was live music at different points along the way. I would stay in Sliema (Bay View/Waterfront hotels are both good). Medal was pretty decent as well but at the time it had different sponsorship. Results done quickly I think. It's worth doing and I may well do this one again in the future. If you are there for a few days around the event, take some time to check out some of the archaeological and architectural gems.
Sorry - I hope I didn't come across as superior or arrogant - that was not my intention. I can only report what I saw on the day and compare it with events I have done and relate it to my local knowledge of the pavements/roads/paths etc.