Granted I don't do massive mileage (about 25 miles a week) but I loved my 2140s and I'm with the comments that got their 2150s out of the box and went running with no problems - no breaking in, no blisters. First run was a 10k tempo run which was about 10 secs off my PB for a pretty hilly training route so it wasn't an easy test. I also don't really feel any weight difference, although perhaps I can say with my 2140s I's have set a new PB.....
1000 miles is very inspiring. I just started a million metres challenge for myself trying to run it in the shortest time I can manage with a year as a backstop. All going well - started on 1 August and have done 20,000 metres already. Maybe I'll see how we go with this one and work up to 1,000 miles in a year next. Best of luck with staying as injury free as you can.
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