Strengths: Though I once did, in fact I tried probably about 5 different makes, all of which ended in blisters, sore toes, hot spots or just plain uncomfortable. Thorlo's solved all these problems - I would not consider wearing anything else!
Weaknesses: Quite expensive. Pale colour so as soon as I've run through a muddy puddle they're a bit stained. Possibly a bit warm in hot weather but they don't make my feet sweat so not too much of an issue