It's a great race, my personal favourite HM. Missed it last year through injury but plan on doing it this year.
The uphills are offset by some downhill sections as well which help make the times comparable with other races. The worst one is miles 10 to 12. There's a short section along the main road and then you turn left into Whirley lane and climb for 2 miles. It's not steep but constant and no respite and hurts after you've already done 10 miles. The earlier ones are more short and sharp, Hocker Lane is probably the steepest around 8 miles in and climbs for about 3/4 mile.
I run through Tatton most weekends. It's pretty muddy and slippy at the moment so trail shoes would probably help, although I don't have any and thus wear road ones. It isn't overly arduous terrain so it's not a problem wearing road shoes.
Good to hear it's full up as it's for local charities. Unfortunately being the same day as Stockport 10 I can't make it. Although the concept of paying to run in Tatton when I do it for free most weekends does seem strange!!
Wincle and Langley - my two favourite races of the year. They are both superb fun, although tough. It's easy to become obsessed with times when entering events but races like those you just forget the times and enjoy them, they really remind you of why we run in the first place.