Nike are a pretty good running brand although some would argue they're over-priced and focus too much on the fashion market rather than purely on function.
The key to finding good running shoes is to ignore the marketing nonsense and go to a good running shop with an open mind. Try different brands, take their advice and find shoes that work for you, i.e. they work with your running style (biomechanics), fit you well and are in your price range. Buying shoes because they look nice and/or they impress your mates isn't really a good idea.
I wear Hoka Bondis. Although they're called "maximal" shoes, this is a bit of a misnomer for lots of the Hoka range.
Shoes like the Bondi are essentially very simple, well cushioned shoes. In a way they're minimal - they have simple uppers and midsoles, generally no control devices or midsole gimmickry - air, gel, torsion systems etc.
Although the midsole looks big, the heel sits down inside it, so the depth of heel cushioning is actually pretty much the same as a "normal" running shoe.
The main difference is the drop is far lower - 4mm (I think) for the Bondi - which means the level of forefoot cushioning is far higher.
Why not give them a try ? I really love them and would struggle to run in anything else now - I find my knees complain in a regular shoe, although I don't think this is as much to do with the amount of cushioning, more the lower drop.
Hoka are fabulous shoes, I would struggle to run in anything else now. The downside can be the fit - they tend to be narrow, although some of the newer models (like the Clifton 3) have a wider forefoot.
As others have said, the Challenger is the trail version of the Clifton. The latest version of it - the Clifton 3 - is just out.
I've found if you use your American shoe size then that works best. So if you look inside the tongue of most shoes there will be a UK, American and European size. For me I take a UK 10, which equates to a US 11. If I order a US 11 then the fit is right.
There are lots of places that stock them now - they were recently bought out by Decker who make Ugg boots, so distribution is improving. I tend to buy online though - normally from ultramarathonrunningstore.com. I've always had great service from them and their returns policy is good. I'm sure if you Google there are lots of others.
In terms of road shoes, the Clifton is a very popular, light shoe. I personally wear the Bondi - I find it a bit more supportive and substantial. The Stinson is the traditional "full" Hoka with maximum cushioning. The Conquest is a heavier, more controlling shoe for over-pronators. I think they have just released some faster racing shoes too, but don't know much about them.