I've got a 220 and am reasonably happy with it. Gets signals quickly, is light and works well.
The pace alerts though are awful. They're all over the place, go off all the time despite me running a steady pace well within the range. I really liked the idea of these but had to turn them off now. Useless.
My 110 is getting a bit old in the tooth. The battery doesn't hold its charge as well as it did and it's not picking up satellites as quickly. Also it's always been a bit temperamental, the clip isn't reliable and the garmin website doesn't seem to work properly with my old laptap (it's xp). It has been great when it's worked but it could be oh so much better.
So what's the alternative? I just want something simple to measure distance and time, see the route on a map, and give me split lap times for every km. Is the Garmin 10 an improvement or is there another brand I should be looking at?