Bit late to the party, but I ran Brighton this year, the advice about headphones was exactly the same as for 2013 and I ran with earphones - as did plenty of other people. I do agree that it can detract from the party atmosphere, but you can take them out/put them in depending on how much musical motivation you need! You won't get disqualified for wearing them.
Brighton's a brilliant marathon - if you can get a charity place, go for it!